Table 3.

Study schedule

Scheduling	Screening and enrolment	Baseline and treatment day 1	Treatment day 2*	48 hours	1 week	3 weeks	6 weeks	12 weeks
	3 weeks before baseline	3 weeks after enrolment	1 day after baseline	2 days after baseline	1 week after baseline	3 weeks after baseline	6 weeks after baseline	12 weeks after baseline
Visit type	Clinic	Clinic	Clinic	Phone call	Phone call	Phone call	Clinic	Clinic
Eligibility screen	✓
Informed consent	✓
FMT treatment		✓	✓
Adverse events			✓	✓	✓	✓	✓	✓
Tolerability questionnaire			✓
Background questionnaire		✓
Eating disorder symptoms (EDEQ)66		✓					✓	✓
Depression symptoms (PHQ-9)60	✓	✓					✓	✓
Anxiety symptoms (GAD-7)67		✓					✓	✓
Stool sample	✓	✓				✓	✓	✓
Blood sample		✓					✓	✓
Whole-body composition scan (DXA)	✓							✓

*Study timeline is based on a 2 day treatment schedule. If a participant decides to spread their treatment over four consecutive days, the tolerability questionnaire will be administered on the final day of treatment (day 4) and the 48 hour phone call will be 24 hours after the final dose of capsules.

DXA, dual-energy X-ray absorptiometry; EDEQ, Eating Disorder Examination Questionnaire; FMT, faecal microbiome transfer; GAD-7, General Anxiety Disorder 7-item scale; PHQ-9, Patient Health Questionnaire 9.