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. 2023 Jul 10;13(7):e069835. doi: 10.1136/bmjopen-2022-069835

Table 3.

Relationship between aggressive treatments and level of treatment aggressiveness before death with palliative care among patients with kidney failure by multivariable regression

OR/estimate 95% CI P value C/R2 Likelihood ratio/F value P value
More than one ED visit within 30 days before death 0.68 0.61 to 0.75 <0.001 0.547 68.13 <0.001
More than one admission within 30 days before death 0.62 0.56 to 0.69 <0.001 0.586 209.65 <0.001
More than 14 days of hospitalisation within 30 days before death 1.19 1.05 to 1.35 0.009 0.573 96.29 <0.001
Admission to ICU within 30 days before death 0.70 0.62 to 0.78 <0.001 0.561 97.69 <0.001
Death in hospital 0.93 0.83 to 1.03 0.152 0.600 308.29 <0.001
ETT within 30 days before death 0.38 0.33 to 0.44 <0.001 0.652 628.76 <0.001
Ventilator use within 30 days before death 0.83 0.69 to 1.01 0.059 0.598 261.75 <0.001
CPR within 30 days before death 0.23 0.18 to 0.28 <0.001 0.669 621.19 <0.001
Aggressiveness rate† −0.09 −0.10 to 0.08 <0.001 0.027 46.26 <0.0001
Aggressiveness rate* −0.06 −0.07 to 0.04 <0.001 0.013 22.67 <0.001
BT within 30 days before death 1.09 0.98 to 1.21 0.127 0.550 69.3917 <0.001
Use of NG, gastrostomy or TPN within 30 days before death 0.91 0.82 to 1.02 0.094 0.554 94.89 <0.001

Adjusted for age, gender, low income, living in rural areas and CCI.

*Consisted of five aggressive treatments, including more than one ED visit within 30 days before death, more than one admission within 30 days before death, a longer than 14-day admission within 30 days before death, admission to ICU within 30 days before death and death in hospital.

†Consisted of eight aggressive treatments, including more than one ED visit within 30 days before death, more than one admission within 30 days before death, a longer than 14-day admission within 30 days before death, admission to ICU within 30 days before death, death in hospital, ETT within 30 days before death, ventilator use within 30 days before death and CPR within 30 days before death.

BT, blood transfusion; CCI, Charlson’s Comorbidity Index; CPR, cardiopulmonary resuscitation; ED, emergency department; ETT, endotracheal tube; ICU, intensive care unit; NG, nasogastric tube; TPN, total parenteral nutrition.