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. 2023 Jun 27;14:1174120. doi: 10.3389/fphar.2023.1174120

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Copyright © 2023 Shafiei, Jafari-Gharabaghlou, Farhoudi-Sefidan-Jadid, Alizadeh, Fathi and Zarghami.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Investigation of drug release efficiency from magnetic nisome nanoparticles (MNNPs) at pH = 5.8 and 7.4 at 37°C. The pores of the dialysis membrane are large enough to allow the free movement of silibinin, but small enough to prevent the diffusion of nanoparticles. The results demonstrated a sustained release pattern from the nanoparticle with a partially burst-release at the initial stage and followed sustained during the 96 h study period. Data are presented as mean ± SD of three independent experiments.