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. 2023 May 5;6(4):e425. doi: 10.1002/edm2.425

FIGURE 3.

FIGURE 3

Evaluation of the effect of a subtotal pancreatectomy on glucose metabolism in Göttingen‐like minipigs. (A) Mean Fasting Blood Glucose (Mean ± SD; n = 10) measured during MMT before (in black) and after (in blue) subtotal pancreatectomy. (B, C) Mean curves (Mean ± SEM; n = 10) of Blood Glucose (B) and Plasma Insulin (C) during MMT before (in black) and after (in blue) subtotal pancreatectomy. (D) Mean Insulinogenic Index (Mean ± SD; n = 10) calculated during MMT before (in black) and after (in blue) subtotal pancreatectomy. (E, F) Mean curves (Mean ± SEM; n = 10) of Blood Glucose (E) and Plasma Insulin (F) during IVGTT before (in black) and after (in blue) subtotal pancreatectomy. (G) Mean Acute Insulin Response (Mean ± SD; n = 10) calculated during IVGTT before (in black) and after (in blue) subtotal pancreatectomy. (H) Fasting plasma lipid profile (Mean ± SD; n = 10) assessed before (in black) and after (in blue) subtotal pancreatectomy. HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; TG, triglycerides; Total Chol, total cholesterol. Two‐Way ANOVA test for repeated measures and Sidak post‐hoc test; Paired t‐test; *p < .05, ***p < .0005 between baseline and after pancreatectomy.