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. 2023 Jun 16;4:uqad032. doi: 10.1093/femsml/uqad032

Figure 1.

Figure 1.

Histone acetylation and deacetylation. The acetylation of histone lysine residues involves the covalent attachment of an acetyl group to the ε-position of the lysine side chain, which creates an open chromatin structure that is more permissible for gene transcription. Lysine deacetylation involves the removal of the acetyl group, leading to a more compacted chromatin structure that is less accessible for active gene expression. Created with BioRender.com.