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. 2023 Jun 16;4:uqad032. doi: 10.1093/femsml/uqad032

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© The Author(s) 2023. Published by Oxford University Press on behalf of FEMS.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — Histone lysine crotonylation, an evolutionarily conserved post-translational epigenetic modification, involves the reversible covalent attachment of a crotonyl group to the ε-amino group of the lysine side chain, and histone lysine decrotonylation involves the removal of the crotonyl group. Several histone acetyltransferases also have histone crotonyltransferase activity, and several histone deacetylases have histone decrotonylation activities as well. Based on information from references (Madsen and Olsen 2012, Bao et al. 2014, Sabari et al. 2015, Liu et al. 2017, Wei et al. 2017, Xu et al. 2017, Fellows et al. 2018, Kollenstart et al. 2019). Created with BioRender.com.