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Flow chart for non-responding patients to second-line chemotherapy and their outcome after further salvage chemotherapy regimens. ICE, ifosfamide, carboplatin and etoposide; GV, gemcitabine and vinorelbine; CR, complete response; PR, partial response; PD, progressive disease; ASCT, autologous stem cell transplantation; FDG-PET, fluorodeoxyglucose (FDG)-positron emission tomography.
