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. 2023 Mar 30;49(3):281–298. doi: 10.1590/S1677-5538.IBJU.2022.0587

Table 2. Characteristics of serum and 24h-urine chemistries of the patients.

  Characteristics Studies Number of patients Heterogeneity Overall effect  
BMI<25 vs BMI≥25(kg/m2) p value I2 (%) WMD (95% CI) p value*
Serum Calcium (mg/dL) [20, 28] 503/301 0.95 0 -0.10 (-0.19, -0.01) 0.03
Urate (mg/dL) [20, 28, 30] 582/604 0.02 75% -0.86 (-1.04, -0.68) <0.00001
24-urine Volume (mL) [19, 20, 30] 1362/1069 0.4 0 -88.49 (-148.02, -28.95) 0.004
pH [14, 19, 20, 28, 31] 2180/2164 <0.00001 98% 0.13(0.09, 0.16) <0.00001
Calcium excretion (mg/day) [20, 30, 31] 1387/1831 0.26 26% -11.47(-19.97, -2.96) 0.008
Oxalate excretion (mg/day) [20, 30, 31] 1387/1831 0.58 0 -1.62(-2.67, -0.57) 0.003
Urate excretion (mg/day) [14, 20, 30, 31] 1423/1858 0.006 76% -88.23(-101.87, -74.59) <0.00001
Citrate excretion (mg/day) [20, 30, 31] 1387/1831 0.1 57% -33.28(-52.16, -14.40) 0.00006

WMD: weighted mean difference, CI: confidence interval

*p <0.05 was considered statistically significant and shown in bold.