Table 2. Characteristics of serum and 24h-urine chemistries of the patients.
Characteristics | Studies | Number of patients | Heterogeneity | Overall effect | |||
---|---|---|---|---|---|---|---|
BMI<25 vs BMI≥25(kg/m2) | p value | I2 (%) | WMD (95% CI) | p value* | |||
Serum | Calcium (mg/dL) | [20, 28] | 503/301 | 0.95 | 0 | -0.10 (-0.19, -0.01) | 0.03 |
Urate (mg/dL) | [20, 28, 30] | 582/604 | 0.02 | 75% | -0.86 (-1.04, -0.68) | <0.00001 | |
24-urine | Volume (mL) | [19, 20, 30] | 1362/1069 | 0.4 | 0 | -88.49 (-148.02, -28.95) | 0.004 |
pH | [14, 19, 20, 28, 31] | 2180/2164 | <0.00001 | 98% | 0.13(0.09, 0.16) | <0.00001 | |
Calcium excretion (mg/day) | [20, 30, 31] | 1387/1831 | 0.26 | 26% | -11.47(-19.97, -2.96) | 0.008 | |
Oxalate excretion (mg/day) | [20, 30, 31] | 1387/1831 | 0.58 | 0 | -1.62(-2.67, -0.57) | 0.003 | |
Urate excretion (mg/day) | [14, 20, 30, 31] | 1423/1858 | 0.006 | 76% | -88.23(-101.87, -74.59) | <0.00001 | |
Citrate excretion (mg/day) | [20, 30, 31] | 1387/1831 | 0.1 | 57% | -33.28(-52.16, -14.40) | 0.00006 |
WMD: weighted mean difference, CI: confidence interval
*p <0.05 was considered statistically significant and shown in bold.