Table 1.
Comparison of mean blood values between cases with SUD evaluated in the study and those in the control group
| Variable | MUD | Control group | Analysis | pvalue | |||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| Mean (median) | SD (25−75%) | Mean (median) | SD (25−75%) | ||||
| Native thiol | 404.73 | 55.99 | 474.50 | 82.73 | t = −4.67 | < 0.001 | |
| Total thiol | 442.13 | 56.33 | 510.77 | 82.15 | t = −4.60 | < 0.001 | |
| Disulfide | 18.70 | 5.62 | 18.13 | 5.03 | t = 0.48 | 0.630 | |
| Disulfide/native thiol (%) | 4.72 | 1.62 | 3.96 | 1.33 | t = 2.31 | 0.024 | |
| Disulfide/total thiol (%) | 4.28 | 1.34 | 3.64 | 1.14 | t = 2.30 | 0.024 | |
| Native thiol/total thiol (%) | 91.45 | 2.68 | 92.72 | 2.29 | t = −2.30 | 0.024 | |
| IMA | 0.84 | 0.83−0.86 | 0.83 | 0.81−0.84 | Z = −3.88 | < 0.001 | |
| IL-6 | 2.37 | 0.48 | 2.28 | 0.33 | t = 0.95 | 0.346 | |
| WBC | 9.12 | 2.64 | 7.56 | 2.14 | t = 2.68 | 0.009 | |
| Hemoglobin | 14.70 | 14.10−15.40 | 15.10 | 14.50−15.70 | Z = −1.37 | 0.172 | |
| Hematocrit | 43.65 | 41.40−46.20 | 44.90 | 42.10−45.50 | Z = −0.90 | 0.366 | |
| Neutrophil | 5.50 | 2.07 | 4.11 | 1.33 | t = 3.22 | 0.002 | |
| Monocyte | 0.70 | 0.21 | 0.49 | 0.17 | t = 4.60 | < 0.001 | |
| PLT | 268.00 | 240.50−316.00 | 236.00 | 204.00−290.00 | Z = −2.62 | 0.009 | |
| Lymphocyte | 2.94 | 0.83 | 2.76 | 0.86 | t = 0.88 | 0.380 | |
| Eosinophil | 0.21 | 0.11−0.33 | 0.14 | 0.10−0.21 | Z = −1.75 | 0.081 | |
| Basophil | 0.02 | 0.01−0.03 | 0.02 | 0.02 | Z = −0.02 | 0.987 | |
| NLR | 1.77 | 1.40−2.28 | 1.52 | 1.27−1.75 | Z = −2.00 | 0.045 | |
| MLR | 0.23 | 0.19−0.30 | 0.16 | 0.14−0.22 | Z = −3.92 | < 0.001 | |
| PLR | 101.30 | 77.50−121.49 | 83.83 | 72.99−105.47 | Z = −1.42 | 0.156 | |
SUD, substance use disorder; MUD, methamphetamine use disorder; IMA, ischemic modified albumin; IL-6, interleukin-6; PLT, platelet; NLR, neutrophil/lymphocyte ratio; MLR, monocytes/lymphocyte ratio; PLR, platelet/lymphocyte ratio; SD, standard deviation; WBC, white blood cell.