Table 1.

Level of evidence for Anhedonia treatments

Treatment	Level of evidence
Agomelatine [42,77-81]	***
Vortioxetine [82-86]	***
Ketamine [50,90]	***
Transcranial magnetic stimulation [94-98]	***
Psylocibine [92]	**
Bupropion (with or without dextromethorphan) [66,67,70]	**
Sertraline and fluoxetine [74,75]	**
Venlafaxine [76]	**
Methylphenidate [93]	**
Cognitive-behavioral therapy, behavioral activation [100]	**
Selective serotonin reuptake inhibitors except sertraline and fluoxetine [19,62,63,72,73]	*
Pramipexole [71]	*

Ranked from * to *** based on empirical evidence.