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. Author manuscript; available in PMC: 2024 May 15.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Apr 21;1223:123725. doi: 10.1016/j.jchromb.2023.123725

Table IV.

Stability of PEth in whole blood, dried blood spots, and extracted samples.

Sample/Stability Condition CV (%) Deviation from Nominal (%) Difference from Control (%) n
Whole Blood1 3.6 NA 2.2 3
Dried Blood Spots
Room
Temperature2
QL 4.0 0.8 7.7 3
QH 7.0 1.8 9.4 3
Freeze-Thaw3 QL 5.9 2.7 1.4 3
QH 9.4 13.1 2.7 3
Long-Term4 QL 5.4 10.4 12.9 3
QH 2.3 7.3 9.4 3
Extracted Samples5
Autosampler QL 10.6 8.0 0.6 6
QH 2.0 5.5 0.4 6
Reinjection QL 11.3 0.9 7.7 6
QH 2.1 4.6 0.4 6
1

Participant whole blood containing PEth was kept at room temperature for 4 days.

2

DBS were kept at room temperature for 7 days.

3

Three freeze-thaw cycles were evaluated with DBS kept at −80 C.

4

Long-term stability was evaluated at 228 days with DBS kept at −80 C.

5

Extracted samples were evaluated after 15 days of storage at 15 C.