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. 2023 Jun 19;55(7):1186–1197. doi: 10.1038/s41588-023-01429-4

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 7 — a, Schematic representation of the colony formation assay. b, Schematic representation of the nested PCR. Two breakpoints of the assayed SV are located >5 kb apart on the same chromosome or on different chromosomes (for example BCR in chr22 and ABL1 in chr9). PCR amplification is successful only when the assayed SV is present. c, Numbers of BCR-ABL1 positive and negative colonies in 14 samples. Subtype and BCR-ABL1 isoform (p210/p190) of each sample are shown.