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. 2023 Jul 11;46(1):169. doi: 10.1007/s10143-023-02081-6

Table 2.

Risk factors of neurogenic pulmonary edema in subarachnoid hemorrhage

First author Publication year Area Risk factors OR 95% CI
Joji Inamasu 2012 Japan Norepinephrine 1.003 1.002–1.007
Eija Junttila 2013 Finland APACHE II score ≥ 20 6.17 1.30–29.21
IL-6 > 40 pg/mL 5.62 1.26–25.08
cTnI > 0.06 μmol/L 4.24 0.97–18.58
Etsuko Satoh 2014 Japan Lactate level 1.04 1.00–1.09
Age 0.9 0.83–0.97
Glucose level 1.03 1.01–1.05
Wei-Lung Chen 2016 China WFNS class * 5.8 2.6–13.3
Abnormal Q or QS wave 3.1 1.1–9.1
nonspecific ST- or T-wave changes 3 1.2–7.5
Wei-Lung Chen 2016 China WFNS class * 4.048 1.589–10.311
Total power(ms2) 0.995 0.992–0.998
Normalized low-frequency component (nu) 0.993 0.910–0.958
Limin Zhang 2016 China corrected QT prolongation 1.5 1.1–2.2
ST depression 2.3 1.0–5.2
nonspecific ST or T-wave change 2.7 1.8–4.2
Tijana Nastasovic 2017 Serbia Female 5.253 1.14–24.16
Hunt and Hess grade ≥ 3 12.593 1.27–124.79
Hydrocephalus 8.075 1.55–42.06
Elevated troponin I 4.862 1.26–18.74
Elevated white blood cell count 21.867 4.02–118.75
Tatsuki Kimura 2020 Japan WFNS grade 3–5 3.73 1.02–13.66
VA dissection 4.83 1.50–15.56

World Federation of Neurological Surgeons (WFNS) class (class I, Glasgow Coma Scale [GCS] = 15, no motor deficit; class II, GCS = 13- 14, no motor deficit; class III, GCS = 13–14, presence of motor deficit; class IV: GCS = 7–12; class V: GCS = 3–6. * The OR for WFNS class represents the OR for each 1-point increase from low-grade WFNS (I-III) to high-grade WFNS (VI-V)