Table 2.
The course of health-related quality of life over time
| Measurement | N | Observed data | Estimated with LMM | p-value | p-value compared to T0/M6 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Median | Interquartile range | Mean | 95% CI | ||||||
| EORTC—global quality of life | |||||||||||
| T0:baseline | 596 | 71.7 | 19.0 | 75.0 | 58.3 | 83.3 | 71.6 | 70.2 | 73.0 | 0.000 | |
| 3 months | 535 | 73.8 | 17.6 | 75.0 | 66.7 | 83.3 | 73.5 | 72.0 | 75.0 | 0.013 | |
| 6 months | 490 | 76.7 | 17.5 | 83.3 | 66.7 | 83.3 | 75.8 | 74.2 | 77.3 | 0.000 | |
| 12 months | 437 | 79.5 | 17.0 | 83.3 | 66.7 | 91.7 | 77.9 | 76.3 | 79.5 | 0.000 | |
| 24 months | 392 | 78.8 | 16.9 | 83.3 | 66.7 | 91.7 | 76.7 | 75.1 | 78.4 | 0.000 | |
| 6 months | 490 | 76.7 | 17.5 | 83.3 | 66.7 | 83.3 | 76.7 | 75.2 | 78.2 | 0.032 | |
| 12 months | 437 | 79.5 | 17.0 | 83.3 | 66.7 | 91.7 | 78.7 | 77.2 | 80.3 | 0.009 | |
| 24 months | 392 | 78.8 | 16.9 | 83.3 | 66.7 | 91.7 | 77.8 | 76.1 | 79.4 | 0.195 | |
| EORTC—summary score | |||||||||||
| T0:baseline | 592 | 86.4 | 11.9 | 89.8 | 80.6 | 95.5 | 86.2 | 85.2 | 87.2 | 0.000 | |
| 3 months | 527 | 83.6 | 13.4 | 87.0 | 75.9 | 93.7 | 83.1 | 82.1 | 84.2 | 0.000 | |
| 6 months | 486 | 86.8 | 11.9 | 89.3 | 81.7 | 95.8 | 86.1 | 85.1 | 87.2 | 0.85 | |
| 12 months | 436 | 88.9 | 11.4 | 91.9 | 84.9 | 97.4 | 87.5 | 86.4 | 88.6 | 0.010 | |
| 24 months | 391 | 88.7 | 10.8 | 91.7 | 83.9 | 96.4 | 87.1 | 86.0 | 88.2 | 0.10 | |
| 6 months | 486 | 86.8 | 11.9 | 89.3 | 81.7 | 95.8 | 86.8 | 85.8 | 87.9 | 0.020 | |
| 12 months | 436 | 88.9 | 11.4 | 91.9 | 84.9 | 97.4 | 88.1 | 87.1 | 89.2 | 0.007 | |
| 24 months | 391 | 88.7 | 10.8 | 91.7 | 83.9 | 96.4 | 87.8 | 86.7 | 88.8 | 0.059 | |