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. 2023 Jul 11;13:11207. doi: 10.1038/s41598-023-36995-4

Table 1.

Clinical characteristics of 132 respondents according to the presence of persistent symptoms or signs identified 24 months after the diagnosis or symptom onset of acute COVID-19.

Characteristics No symptom (N = 38) Symptom (N = 94) Total (N = 132) P-value
Days from COVID-19 diagnosis to survey 820.0 [816.0;821.0] 819.0 [816.0;823.0] 819.0 [816.0;823.0] 0.493
Sex 0.159
 Male 16 (42.1%) 26 (27.7%) 42 (31.8%)
 Female 22 (57.9%) 68 (72.3%) 90 (68.2%)
Age, median (IQR; years) 29.5 [23.0;47.0] 40.0 [25.0;52.0] 38.0 [24.0;50.5] 0.097
Age distribution (years) 0.295
 18–29 19(50.0%) 32(34.0%) 51 (38.6%)
 30–39 4 (10.5%) 15 (16.0%) 19 (14.4%)
 40–49 9 (23.7%) 18 (19.1%) 27 (20.5%)
 50–59 4 (10.5%) 19 (20.2%) 23 (17.4%)
 60–70 2 (5.3%) 10 (10.6%) 12 (9.1%)
Age (years) 0.119
 < 50 32 (84.2%) 65 (69.1%) 97 (73.5%)
 ≥ 50 6 (15.8%) 29 (30.9%) 35 (26.5%)
Disease severity 0.002
 Asymptomatic 7 (18.4%) 2 (2.1%) 9 (6.8%)
 Mid 29 (76.3%) 73 (77.7%) 102 (77.3%)
 Moderate 2 (5.3%) 17 (18.1%) 19 (14.4%)
 Severe 0 (0.0%) 2 (2.1%) 2 (1.5%)
 Critical 0 (0.0%) 0 (0.0%) 0 (0.0%)
Disease severity 0.062
 < Moderate 36 (94.7%) 75 (79.8%) 111 (84.1%)
 ≥ Moderate 2 (5.3%) 19 (20.2%) 21 (15.9%)
Isolation placea 0.046
 Secondary or tertiary hospital 14 (36.8%) 57 (60.6%) 71 (53.8%)
 Therapeutic living center 22 (57.9%) 34 (36.2%) 56 (42.4%)
 Self-home isolation 2 (5.3%) 3 (3.2%) 5 (3.8%)
Oxygen treatment 0.626
 Yes 0 (0.0%) 2 (2.1%) 2 (1.5%)
 No 38 (100.0%) 92 (97.9%) 130 (98.5%)
Newly diagnosed diseases following acute COVID-19 0.016
 Yes 0 (0.0%) 16 (17.0%) 16 (12.1%)
 No 38 (100.0%) 78 (83.0%) 116 (87.9%)
Outpatient clinic visits due to long COVID 0.146
Yes 0 (0.0%) 8 (8.5%) 8 (6.1%)
No 38 (100.0%) 86 (91.5%) 124 (93.9%)
COVID-19 vaccination historyb 1.000
 Yes 37 (97.4%) 90 (95.7%) 127 (96.2%)
 No 1 (2.6%) 4 (4.3%) 5 (3.8%)
Number of COVID-19 vaccination 1.000
 < 2 2 (5.3%) 5 (5.3%) 7 (5.3%)
 ≥ 2 36 (94.7%) 89 (94.7%) 125 (94.7%)
Number of COVID-19 vaccination 0.454
 0 1 (2.6%) 4 (4.3%) 5 (3.8%)
 1 1 (2.6%) 1 (1.1%) 2 (1.5%)
 2 10 (26.3%) 26 (27.7%) 36 (27.3%)
 3 18 (47.4%) 31 (33.0%) 49 (37.1%)
 4 8 (21.1%) 32 (34.0%) 40 (30.3%)

COVID-19 coronavirus disease 2019, IQR interquartile range.

aIsolation place: the place where patients were quarantined after being diagnosed with COVID-19 for the first time.

bAll respondents had received COVID-19 vaccination following acute COVID-19.