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. 2023 Jul 11;13:11207. doi: 10.1038/s41598-023-36995-4

Table 2.

Univariate and multivariate logistic regression analyses for the factors associated with long COVID 24 months following COVID-19.

Persistent symptoms or signs Factors Univariate OR Multivariate OR
95% CI P-value 95% CI P-value
Fatigue  ≥ Moderate severity 3.02 (1.17–8.05) 0.023 3.02 (1.17–8.05) 0.023
 ≥ 50 years old 1.35 (0.60–3.00) 0.456
Female 0.95 (0.44–2.06) 0.887
Anxiety  ≥ Moderate severity 2.07 (0.66–5.87) 0.185 2.07 (0.66–5.87) 0.185
 ≥ 50 years old 1.18 (0.42–3.04) 0.745
Female 0.92 (0.37–2.46) 0.86
Depression  ≥ Moderate severity 1.82 (0.59–5.11) 0.270 1.85 (0.55–5.77) 0.297
 ≥ 50 years old 1.30 (0.49–3.26) 0.587 1.30 (0.49–3.26) 0.885
Female 1.34 (0.53–3.70) 0.551 1.34 (0.53–3.70) 0.478
Insomnia  ≥ Moderate severity 1.71 (0.56–4.79) 0.319
 ≥ 50 years old 2.32 (0.94–5.65) 0.065 2.32 (0.94–5.65) 0.065
Female 1.14 (0.46–2.99) 0.784
Concentration difficulty  ≥ Moderate severity 2.23 (0.80–5.94) 0.112 1.80 (0.60–5.14) 0.281
 ≥ 50 years old 2.01 (0.84–4.70) 0.109 1.69 (0.66–4.19) 0.264
Female 1.26 (0.54–3.15) 0.607
Cognitive dysfunction  ≥ Moderate severity 2.14 (0.54–7.11) 0.235 1.70 (0.39–6.37) 0.451
 ≥ 50 years old 2.02 (0.63–6.11) 0.216 1.71 (0.48–5.63) 0.382
Female 0.93 (0.31–3.14) 0.874 0.98 (0.32–3.40) 0.969
Amnesia  ≥ Moderate severity 1.94 (0.73–5.04) 0.177 1.54 (0.52–4.42) 0.424
 ≥ 50 years old 2.56 (1.14–5.79) 0.023 2.31 (0.96–5.55) 0.059
Female 1.93 (0.84–4.74) 0.133 2.07 (0.88–5.28) 0.109
Anosmia  ≥ Moderate severity 4.12 (0.97–15.99) 0.042 2.45 (0.51–10.70) 0.238
 ≥ 50 years old 4.81 (1.29–19.94) 0.021 3.61 (0.85–16.23) 0.080
Female 1.95 (0.46–13.33) 0.411
Ageusia  ≥ Moderate severity 4.99 (1.14–20.75) 0.026 2.72 (0.55–12.69) 0.203
 ≥ 50 years old 6.48 (1.61–32.26) 0.011 4.70 (1.02–25.25) 0.051
Female 1.69 (0.39–11.67) 0.526

CI confidence interval, COVID-19 coronavirus disease 2019, OR odds ratio.