Table 2:
Patient Characteristics
| Granulation Tissue Biopsies (qPCR) | Granulation Tissue Dissociations (FC) | iLTS Biopsies (qPCR) | |
|---|---|---|---|
| Enrollment | n=8 | n=4 | n=5 |
| Mean age (SD) | 40.6 (10.2) | 40.3 (11.6) | 51 (10.2) |
| Sex, female (%) | 6 (75%) | 3 (75%) | 5 (100%) |
| BMI (SD) | 40.3 (11.2) | 37.4 (15.5) | 34.4 (8.6) |
| Race/Ethnicity (%) | |||
| Caucasian | 1 (12.5%) | 0 (0%) | 3 (60%) |
| African American | 5 (62.5%) | 4 (80%) | 1 (20%) |
| Asian | 1 (12.5%) | 1 (20%) | 1 (20%) |
| Other | 1 (12.5%) | 0 (0%) | 0 (0%) |
| History of tracheostomy (%) | 8 (100%) | 5 (100%) | 5 (100%) |
| Tracheostomy duration, months (SD) | 16 (12.7) | 21.2 (18.3) | 9.8 (13.8) |
| Intubation duration, days (SD) | 6.2 (2.7) | 5 (0) | 10 (6.1) |
| Charlson Comorbidity Index (SD) | 0.75 (1.4) | 0.75 (1.5) | 3 (2.2) |
| Comorbidities (%) | |||
| Hypertension | 1 (12.5%) | 1 (20%) | 4 (80%) |
| Diabetes | 1 (12.5%) | 1 (20%) | 2 (40%) |
| CAD | 0 (0%) | 1 (20%) | 1 (20%) |
| Months followed* (SD) | 16 (11.4) | 18 (14.6) | 9.8 (8.2) |
| Etiology (%) | |||
| Iatrogenic, post-intubation | 1 (12.5%) | 1 (20%) | 1 (20%) |
| Iatrogenic, post-tracheostomy | 0 (0%) | 1 (20%) | 1 (20%) |
| Iatrogenic, post-intubation and tracheostomy | 6 (75%) | 3 (60%) | 3 (60%) |
| Idiopathic | 1 (12.5%) | 0 (0%) | 0 (0%) |
SD=standard deviation
PCR=polymerase chain reaction
FC=flow cytometry
iLTS=iatrogenic laryngotracheal stenosis
*
months followed calculated from time of first clinic visit to procedure