Curricular considerations |
1 |
Education across the fellowship should incorporate both slides derived from patients under the care of the fellow as well as slides from formal slide libraries of high yield morphologies |
2 |
Trainees should be well versed in the description of normal and pathologic nuclear and cytoplasmic characteristics |
3 |
Curricula should include education on how PBS review can augment, or potentially eliminate the need for, more advanced testing |
4 |
Discussions of the practical use of PBS review should occur within the context of the medical system as a whole with specific attention devoted to discussions of:
-
(a)
Avoiding clinically relevant delays in diagnosis and treatment
-
(b)
Providing care in resource limited settings
-
(c)
Cost of care and financial toxicity of advanced diagnostic testing
|
5 |
Trainees should be aware of and familiar with intracellular parasites (malaria, babesia, ehrlichia/anaplasma) regardless of their geographic location of training |
Method of review |
1 |
Trainees should be taught to systematically review a PBS. This includes specific education on identification of the monolayer, use of various magnifications, switching between magnification, and systematic review of each cell line |
2 |
Learners should be competent in the personal use of a compound light microscope, and should receive hands on training throughout fellowship |
3 |
Learners should be made aware of limitations associated with the use of digital and remote microscopy use |
Morphology |
1 |
Emphasis should be placed on
-
(a)
Disorders where correct and timely diagnosis is paramount to avoiding significant patient morbidity, acute decompensation, or death
-
(b)
Commonly encountered diagnoses
|
2 |
Trainees should be able to identify features of normal PBSs |
3 |
Specific curricular emphasis should be placed on the morphologic presentation of acute leukemias and hemolytic anemias, including TMA |
Disorders of white blood cells |
Trainees should be able to: |
1 |
Distinguish reactive leukocytosis from malignant processes |
2 |
Identify blasts and myeloid precursors |
3 |
Recognize evidence of myeloid dysplasia in peripheral blood |
4 |
Identify the following cells on a PBS: atypical (reactive) lymphocytes, large granular lymphocytes, mature lymphocytes, mature myeloid cells, and immature myeloid precursors |
5 |
Identify circulating promyelocytes, specifically in the context of suspected acute promyelocytic leukemia |
Disorders of red blood cells |
Trainees should be able to: |
1 |
Readily identify peripheral smear evidence of TMA, with specific emphasis on identification of schistocytes |
2 |
Hypothesize the mechanism of hemolytic anemia based upon red blood cell morphology and the presence of poikilocytes |
3 |
Identify sickle cell morphology |
4 |
Identify morphologic findings seen in thalassemias, specifically in the absence of other clinical data such as family history, hemoglobin electrophoresis, and genetic testing |
Disorders of platelets |
Trainees should be able to: |
1 |
Identify platelet clumping (satellitism) |
2 |
Recognize variation in platelet size |
3 |
Identify relative thrombocytosis or thrombocytopenia |
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All statements had unanimous consensus and exceeded the prespecified threshold (>70%) for strong consensus. |