Fig. 3. Ctnnb1 is dispensable for the post-mitotic retinal pigment epithelium (RPE).
Pictures of the eyes and H&E staining images of the eye sections of embryonic day 14.5 (E14.5) mice, which express wild-type and functional variants of Ctnnb1, are provided in the first and second rows, respectively. Expression of R26EYFP Cre recombinase reporter (third row) and Ctnnb1 (fourth and fifth rows) in the mouse eyes were examined by immunostaining of EYFP and Ctnnb1, respectively. Images in the fifth row show magnified versions of the boxed areas in the fourth row. The eye sections were also immunostained with the antibodies against specific markers to identify the distribution of corresponding cell types. D, dorsal; V, ventral; N, nasal; T, temporal. Scale bars = 500 μm (first row), 50 μm (fifth row), and 100 μm (the rest rows).