Table 2. Hazard Ratios With HOLC Grade and Major Adverse Cardiovascular Events and All-Cause Mortality.
| Variable | Model 1a | Model 2b | Model 3c | |||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |
| Major adverse cardiovascular event | ||||||
| HOLC A | 1 [Reference] | 1 [Reference] | 1 [Reference] | |||
| HOLC B | 0.957 (0.909-1.007) | .09 | 1.002 (0.951-1.055) | .93 | 0.967 (0.917-1.020) | .22 |
| HOLC C | 0.976 (0.930-1.024) | .32 | 1.051 (1.001-1.104) | .04 | 0.991 (0.943-1.042) | .73 |
| HOLC D | 1.02 (0.978-1.080) | .26 | 1.139 (1.083-1.198) | <.001 | 1.056 (1.004-1.110) | .02 |
| All-cause mortality | ||||||
| HOLC A | 1 [Reference] | 1 [Reference] | 1 [Reference] | |||
| HOLC B | 0.944 (0.895-0.995) | .03 | 1.001 (0.948-1.056) | .97 | 0.960 (0.913-1.011) | .63 |
| HOLC C | 0.954 (0.908-1.003) | .06 | 1.050 (0.998-1.105) | .06 | 0.977 (0.931-1.025) | .25 |
| HOLC D | 0.989 (0.940-1.040) | .67 | 1.129 (1.072-1.190) | <.001 | 1.055 (1.001-1.111) | .02 |
Abbreviation: HOLC, Home Owners’ Loan Corporation.
a
Model 1, unadjusted.
b
Model 2, adjusted for age, sex, race and ethnicity.
c
Model 3, adjusted for age, sex, race and ethnicity, diabetes, chronic obstructive pulmonary disease, hypertension, atrial fibrillation, heart failure, baseline low-density lipoprotein cholesterol level, prior myocardial infarction, prior percutaneous coronary intervention, obesity, chronic kidney disease, and the community deprivation index score.