Table 1.
Parameter | Non-survivors | Survivors | Total | p-value | |
No. of patients | 54 (46.6%) | 62 (53.4%) | 116 (100%) | - | |
Gender | Male | 28 (51.9%) | 30 (48.4%) | 58 (50%) | 0.71 |
Female | 26 (48.1%) | 32 (51.6%) | 58 (50%) | ||
Co-morbidities | Diabetes | 15 (27.8%) | 26 (41.9%) | 41 (35.3%) | 0.11 |
Hypertension | 15 (27.8%) | 18 (29.0%) | 33 (28.4%) | 0.88 | |
IHD | 5 (9.3%) | 6 (9.7%) | 11 (9.4%) | 0.93 | |
CVD | 3 (5.6%) | 1 (1.6%) | 8 (6.8%) | 0.24 | |
Hypothyroidism | 2 (3.7%) | 6 (9.7%) | 3 (2.5%) | 0.205 | |
Bronchial Asthma | 1 (1.9%) | 2 (3.2%) | 3 (2.5%) | 0.64 | |
Cause for sepsis | Bronchopneumonia | 26 (48.1%) | 26 (41.9%) | 52 (44.8%) | - |
Urosepsis | 7 (12.9%) | 19 (30.6%) | 26 (22.4%) | ||
CNS | 3 (5.5%) | 12 (19.3%) | 15 (12.9%) | ||
GI and Hepatobiliary | 5 (9.2%) | 3 (4.8%) | 8 (6.8%) | ||
Miscellaneous | 13 (24.07%) | 2 (3.2%) | 15 (12.9%) | ||
Culture | Positive | 22 (40.7%) | 22(35.5%) | 44(37.9%) | 0.56 |
Blood culture | Positive | 9 (16.7 %) | 7 (11.3 %) | 16 (13.8 %) | - |
Negative | 45 (83.3 %) | 55 (88.7 %) | 100 (86.2%) | ||
Organisms isolated from blood culture |
E. coli | 6(11.1 %) | 1(1.6 %) | 7 (6.0 %) | - |
P. aeruginosa | 1(1.8 %) | 2 (3.2 %) | 3 (2.5 %) | ||
Enterococcus | 0 | 2 (3.2 %) | 2 (1.7 %) | ||
CNSA | 0 | 2 (3.2 %) | 2 (1.7 %) | ||
MSSA | 2(3.7 %) | 0 | 2 (1.7 %) | ||
Urine culture | Positive | 8 (14.8%) | 8 (12.9 %) | 16 (13.8 %) | - |
Negative | 46 (87.1%) | 54 (85.2 %) | 100 (86.2%) | ||
Organisms isolated from urine culture |
E. Coli | 5(14.8 %) | 8(12.9 %) | 13 (11.2 %) | - |
C. ferundii | 0 | 1 (1.6 %) | 1 (0.86 %) | ||
Enterococcus | 2(3.7 %) | 0 | 2 (1.7 %) | ||
Sputum culture | Positive | 4 (7.4 %) | 3 (4.8 %) | 7 (6 %) | - |
Negative | 50 (92.6 %) | 59 (95.2 %) | 109 (94 %) | ||
Organisms isolated from sputum culture |
E. Coli | 1 (1.8 %) | 1 (1.6 %) | 13 (11.2 %) | - |
P. aeruginosa | 1 (1.8 %) | 1 (1.6 %) | 1 (0.86 %) | ||
Acinetobacter | 1 (1.8 %) | 1 (1.6 %) | 2 (1.7 %) | ||
Klebsiella | 1 (1.8 %) | 0 | 1(0.8 %) | ||
Inotropic support | Yes | 38 (62.29%) | 23 (37.70%) | 61 (52.6%) | 0.001* |
Mechanical ventilation | Yes | 49 (71.01%) | 20 (28.98%) | 69 (59.5%) | 0.001* |
Group | Sepsis | 16 (29.63%) | 39 (62.9%) | 55 (47.41%) | 0.0003* |
Septic Shock | 38 (70.37%) | 23 (37.1%) | 61 (52.59%) |
Abbreviations: *Significant at 5% level of significance; C. ferundii = Citrobacter ferundii; CNS = Central nervous system; CNSA = Coagulase-negative Staphylococcus aureus; CVD = Cardiovascular disease; E. coli = Escherichia coli, GI = Gastrointestinal; IHD = Ischemic heart disease; MSSA = Methicillin-resistant Staphylococcus aureus; P. aeruginosa = Pseudomonas aeruginosa