Spearman rank correlations between chronological age and second-generation DNAm markers at baseline. DNAm, DNA methylation. aDNAmPhenoAge is a validated novel epigenetic clock that predicts varying aging outcomes, including all-cause mortality, cancers, healthspan, physical functioning, and Alzheimer’s disease [4]. bDNAmGrimAge is a validated novel DNAm biomarker which predicts lifespan and all-cause mortality [5]. cDNAmTL is a DNA methylation measurement of telomere length (unit is per 100-base pairs) [6].