Fig. 1 |. RNA m⁶A landscapes of mouse oocytes and embryos.

a, m⁶A immunofluorescence staining. Experiments were repeated three times. b, Genome browser snapshot of picoMeRIP-seq read density in exonic regions of representative gene transcripts for the indicated oocyte and embryo stages. The oocyte and embryo cartoons were created with BioRender.com. c, PCA on 12 picoMeRIP-seq experiments from indicated oocyte and embryo stages. d, Number of m⁶A peaks. e, Metagene profiles of m⁶A peak distribution. f, Relative enrichment of m⁶A peaks for indicated genomic features. For each feature, the enrichment score was calculated as the log₂ ratio of the observed over expected peak numbers. The colors of samples are the same as those in e. g, Consensus motifs on m⁶A peaks identified in biological replicate 1.