A. Boxplot comparing the mean (with associated 25th and 75th quantiles) percent pancreatic involvement of fibroinflammatory infiltrate/PanIN at 5 months for normal circadian KC (n= 36) and chronic jetlag KC mice (n = 26). B. Representative H&E images of normal circadian (upper) and chronic jetlag (lower) mice at 40x (left) and 100x (right). Scale bars are shown for reference. [Annotation: PanIN (P), acinar (A) cells, islet (I) cells, ductal (D) cells, vascular (V) cells (i.e. endothelial cells), and fibroinflammatory (F) infiltrate]