Table 5.

As per Tables 3 and 4, with genes-and-microbes model data. Top ranking features with p-values less than 0.05 and their importance scores discovered by our genes-and-microbes model (Left). Side-paired differential expression (fold change) analysis results of TPM and CPM values for the same features (Right) Wilcoxon-rank sum test was used to calculate p-values and FDR (Benjamini & Hochberg)

Model Feature Importance Metrics					Differential Expression
Rank	ENSG ID_Gene/Tax ID_Name	Importance Score	Log Importance Score	p-value	Log2 FC	p-value	FDR	Associated Side
1	ENSG00000142661_MYOM3	0.037	-3.29	0	-0.62	1.36E-08	2.71E-08	Left
2	ENSG00000198353_HOXC4	0.033	-3.40	0	1.88	2.11E-15	3.23E-14	Right
3	33043_Coprococcus eutactus	0.027	-3.62	0	2.08	2.00E-14	1.54E-13	Right
4	ENSG00000159182_PRAC1	0.024	-3.72	0	-2.86	5.08E-21	2.34E-19	Left
5	ENSG00000260597_AC012531.25	0.020	-3.90	0	1.19	4.26E-12	2.17E-11	Right
6	33038_[Ruminococcus] gnavus	0.016	-4.13	0	2.07	1.31E-15	3.02E-14	Right
7	ENSG00000184719_RNLS	0.011	-4.50	0.01	-0.89	2.85E-10	9.37E-10	Left
8	ENSG00000197757_HOXC6	0.011	-4.54	0	1.28	5.02E-12	2.31E-11	Right
9	ENSG00000144451_SPAG16	0.010	-4.61	0	-0.64	9.00E-09	1.97E-08	Left
10	851_Fusobacterium nucleatum	0.010	-4.62	0	1.67	2.73E-06	3.49E-06	Right
11	ENSG00000273374_RP11-383I23.2	0.010	-4.62	0	-1.02	2.86E-08	5.47E-08	Left
12	446043_uncultured Lachnospira sp.	0.010	-4.63	0	1.46	5.97E-09	1.37E-08	Right
13	165179_Prevotella copri	0.009	-4.66	0	1.6	1.50E-09	3.85E-09	Right
14	154288_Turicibacter sanguinis	0.009	-4.67	0	1.9	5.00E-08	8.51E-08	Right
15	59620_uncultured Clostridium sp.	0.009	-4.67	0	1.09	6.86E-12	2.87E-11	Right