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. 2023 Jul 11;23:1330. doi: 10.1186/s12889-023-16261-y

Table 2.

Modeled effects of sexual abuse and substance use on depressive symptoms, daily headache and use of medication

Depressive symptoms Daily headache High medication use
Males
OR (95% CI)
Females
OR (95% CI)
Males
OR (95% CI)
Females
OR (95% CI)
Males
OR (95% CI)
Females
OR (95% CI)
Exposure variables Sexual abuse 3.8 (2.5–5.8)*** 2.9 (2.4–3.5) *** 5.3 (2.8–10.1)*** 1.9 (1.5–2.4)*** 3.2 (1.7-6.0)*** 2.0 (1.6–2.6)***
Alcohol intoxication 0.8 (0.6–1.1) 1.0 (0.8–1.2) 1.0 (0.6–1.8) 1.1 (0.8–1.4) 1.5 (1.0-2.4) 1.1 (0.9–1.5)
Smoking 1.2 (0.9–1.6) 1.7 (1.4-2.0)*** 0.9 (0.5–1.5) 1.5 (1.1–1.9)** 1.5 (1.0-2.4) 1.6 (1.3–2.1)***
Cannabis use 2.0 (1.6–2.6)*** 1.5 (1.2–1.9)*** 1.8 (1.1–2.9)* 1.3 (1.0-1.7) 1.6 (1.0-2.5)* 1.2 (0.9–1.6)
Control variables FAS 0.8 (0.7–0.8)*** 0.8 (0.8–0.8)*** 0.9 (0.8-1.0)* 0.9 (0.8-1.0)** 0.9 (0.8-1.0) 1.0 (0.9–1.1)
Age 1.0 (0.9–1.2) 1.0 (0.9–1.1) 1.0 (0.8–1.3) 0.9 (0.8-1.0)** 0.8 (0.7-1.0) 0.9 (0.8-1.0)

Note: *p < 0.05, ** p < 0.01, ***p < 0.001