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. 2023 Jun 12;25:e45135. doi: 10.2196/45135

Table 2.

Change in intervention outcomes over time (n=103).

Variable and condition Preintervention time point (week 0), mean (SD) Postintervention time point (week 9), mean (SD) Follow-up (week 21), mean (SD) η2a P valueb Cohen d (week 0 vs week 9) P valuec Cohen d (week 0 vs week 21) P valued
GAD-7e

DMHf (n=42) 10.98 (5.32) 3.88 (4.68) 3.71 (4.50) 0.40 <.001 1.43 <.001g 1.49 <.001g

DMH+LIh (n=29) 12.03 (4.95) 4.28 (5.40) 3.86 (6.48) 0.45d <.001 1.52 <.001g 1.44 <.001g

DMH+HIi (n=32) 11.47 (5.25) 7.50 (4.22) 6.50 (5.08) 0.28 <.001 0.82 .001 0.90 .02g
PHQ-9j

DMH (n=42) 13.14 (4.64) 4.62 (5.00) 4.62 (5.58) 0.45d <.001 1.79 <.001g 1.68 <.001g

DMH+LI (n=29) 12.45 (5.72) 4.55 (6.31) 4.52 (7.41) 0.45d <.001 1.34 <.001g 1.22 <.001g

DMH+HI (n=32) 13.03 (5.51) 6.95 (3.96) 6.86 (4.19) 0.38d <.001 1.23 <.001 1.13 .01g
Quality-of-life health rating

DMH (n=42) 3.43 (0.99) 4.00 (0.86) 4.12 (0.83) 0.23d <.001 −0.60h,i .004 −0.73d,i <.001

DMH+LI (n=29) 3.62 (1.21) 4.06 (1.20) 4.07 (1.54) 0.13 .12 −0.36l .06 −0.33l .07

DMH+HI (n=32) 3.53 (1.02) 4.18 (0.80) 4.43 (0.94) 0.32h .001 −0.70d <.001 −0.85j .01
Quality-of-life utility index

DMH (n=42) 0.57 (0.18) 0.61 (0.18) 0.68 (0.18) 0.21h .003 −0.24 .32g −0.61 <.001g

DMH+LI (n=29) 0.51 (0.21) 0.64 (0.25) 0.60 (0.28) 0.22j .03 −0.58h .001 −0.35l .09

DMH+HI (n=32) 0.56 (0.23) 0.70 (0.17) 0.67 (0.19) 0.27h .005 −0.65h .004 −0.46 .10
Social support

DMH (n=42) 2.93 (0.87) 3.18 (0.98) 3.08 (1.06) 0.03 .50 −0.27i .08 −0.16i .30

DMH+LI (n=29) 2.86 (0.99) 3.12 (1.27) 3.20 (1.32) 0.02 .78 −0.23 .74 −0.30 .74

DMH+HI (n=32) 2.97 (1.09) 3.27 (1.20) 3.00 (1.04) 0.15 .07 −0.27 .18 −0.03 .92
Sleep hour

DMH (n=42) 405.83 (70.81) 434.21 (69.79) 440.52 (56.87) 0.19h .005 −0.40 .007g −0.52 .01g

DMH+LI (n=29) 442.24 (78.42) 435.88 (75.09) 463.93 (98.53) 0.06 .43 0.08 .62 −0.24 .06

DMH+HI (n=32) 425.31 (79.64) 437.59 (61.09) 431.79 (59.47) 0.07 .31 −0.17 .15 −0.08 .79
Physical health rating

DMH (n=42) 3.50 (0.99) 3.57 (0.88) 4.00 (0.82) 0.08 .12 −0.07 .91g −0.53 .08g

DMH+LI (n=29) 3.38 (1.27) 3.41 (1.37) 3.71 (1.33) 0.06 .47 0.02 .67 −0.25 .22

DMH+HI (n=32) 3.13 (1.18) 3.64 (1.05) 3.57 (1.02) 0.36d <.001 −0.45h .001 −0.37h .005
Mental health rating

DMH (n=42) 2.62 (0.66) 3.64 (0.91) 3.68 (0.80) 0.45d <.001 −1.32 <.001g −1.45 <.001g

DMH+LI (n=29) 2.45 (0.74) 3.29 (0.99) 3.29 (1.54) 0.31h .005 −1.00d <.001 −0.76j .02

DMH+HI (n=32) 2.56 (0.84) 3.55 (0.91) 3.57 (1.02) 0.38d <.001 −1.13d <.001 −1.06j .03

aEffect size was based on repeated measure.

bP value was based on repeated measure ANOVA.

cP value was based on one-tailed paired t test to compare outcome value at week 0 and week 9.

dP value was based on one-tailed paired t test to compare outcome value at week 0 and week 21.

eGAD-7: 7-item Generalized Anxiety Disorder Scale.

fDMH: digital mental health.

gP value was based on one-tailed Wilcoxon signed rank test.

hLI: low-intensity therapist assistance.

iHI: high-intensity therapist assistance.

jPHQ-9: 9-item Patient Health Questionnaire.