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. 2023 Jul 11;24(1):2226353. doi: 10.1080/15384047.2023.2226353

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© 2023 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 1. — (a) the two violin plots show that KLF4 is significantly downregulated in the colon cancer tissue samples; (b-c) the two Kaplan-Meier survival analysis show that patients with low expression of KLF4 in colon cancer have relatively shorter overall survival and disease-free survival; (d) the expression of KLF4 in three colon cancer cell lines (SW480, HCT116, SW620) were lower than normal colon fibroblast CCD-18Co, detected by qRT-PCR and western blot; (e) the expression of KLF4 in SW620/FU and HCT116/FU were lower than SW620 and HCT116, detected by qRT-PCR and western blot.