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. 2023 Jul 11;24(1):2226353. doi: 10.1080/15384047.2023.2226353

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© 2023 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 3. — (a) Protein expression of LC3II/LC3I was significantly increased, and the p62 protein level was decreased in SW620/FU and HCT116/FU; (b) Overexpression of KLF4 significantly inhibited the expression of LC3II/LC3I in SW620/FU and HCT116/FU, and promoted the expression of p62; (c-d) Immunofluorescence analysis shows a significant decrease in LC3 after overexpression of KLF4 in SW620/FU and HCT116/FU.