Figure 5.
(a-c) Four groups, the tumor weight and volume were dramatically reduced in 5-FU+oe-KLF4 group; (d-e) the expression levels of KLF4 in the 5-FU+oe-KLF4 group were significantly increased tested by Qrt-PCR and western blot; (f) Ki67 positive tumor cells was dramatically attenuated in 5-FU+oe-KLF4 group by Immunohistochemistry; (G) LC3 II formation was significantly reduced in 5-FU+oe-KLF4 group by western blot.