Skip to main content
. 2016 Feb 5;2016(2):CD008919. doi: 10.1002/14651858.CD008919.pub2

Bordbar 2008.

Methods Allocation: randomised, no further details
 Blindness: no further details.
 Duration: six weeks
 Setting: inpatients, Iran
 Design: parallel, three groups
Participants Diagnosis: schizophrenia (DSM‐IV) + PANSS negative >14.
 N = 80 (10 excluded).
 Sex: 45M, 45 F.
 Age: average ˜ 48 yrs
Interventions 1. Selegiline: 5 mg / day. N = 25
2. Selegiline: 10 mg/day. N = 25.
 3. Placebo. N = 30.
Stable neuroleptic medication:
Outcomes Leaving the study early.
Mental state: PANSS (negative and positive endpoint scores).
Unable to use: safety (not reported).
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "Table of random numbers".
Allocation concealment (selection bias) Unclear risk No further information.
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk "Identical placebo".
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No further information.
Incomplete outcome data (attrition bias) 
 All outcomes High risk Completer analysis, 10 patients excluded.
Selective reporting (reporting bias) Low risk Main outcomes reported.
Other bias Low risk None obvious.