Doruk 2008.
Methods | Allocation: randomised. Blindness: double‐blind Duration: 12 weeks. Setting: outpatients, Turkey. Design: parallel. |
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Participants | Diagnosis: schizophrenia (SCID), treatment‐resistant. N = 46. Sex: 17F, 29M. Age: average 30 years (Ginko EGb), 32 years (placebo). | |
Interventions | 1. Ginkgo EGb, 120 mg/day. N = 23. 2. Placebo. N = 23. Stable neuroleptic medication: clozapine. | |
Outcomes | Leaving the study early. Mental state: BRPS, SAPS, SANS change scores. Unable to use: adverse effects (not reported). |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Random allocation, no details. |
Allocation concealment (selection bias) | Unclear risk | No details. |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Double‐blind. |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Blinded rater. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Four people who left early were excluded from analysis. |
Selective reporting (reporting bias) | Low risk | Main outcomes reported. |
Other bias | Low risk | None obvious. |