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. 2016 Feb 5;2016(2):CD008919. doi: 10.1002/14651858.CD008919.pub2

Ritsner 2010.

Methods Allocation: randomised.
 Blindness: double‐blind.
 Duration: 8 weeks.
 Setting: outpatients, Israel
 Design: parallel.
Participants Diagnosis: schizophrenia (n = 19) or schizoaffective disorder (n = 5) (DSM‐IV).
 N = 32.
 Sex: 6F, 18M (8 excluded not reported).
 Age: average ˜ 36 years.
Interventions 1. DHEA (400 mg/day), N =13
 2. Placebo. N =11 .
 Stable neuroleptic medication: mixed antipsychotics.
Outcomes Leaving the study early.
Mental state: PANSS.
General functioning: GAF endpoint score.
Unable to use: adverse effects (not reported).
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "random number generation"
Allocation concealment (selection bias) Low risk "allocation details coded and kept confidential"
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk "identical capsules"
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No further information.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Eight patients who discontinued the protocol followed up, but excluded from efficacy analysis.
Selective reporting (reporting bias) Low risk Main outcomes reported.
Other bias Low risk None obvious.