Table 1.

Comparison between laboratory values before and after holding rhGH.

	Normal range	On rhGH	2 months off rhGH
IGF-1 (ng/mL)	220–574*	558
IGF-1 z-score	−2.0 to +2.0	+2.0
HbA1c (%)		11.7	5.7
IA-2 Ab (U/mL)	0–0.8, 0–7.4	8.5	>120.0
Insulin Ab (U/mL)	0–0.4	<0.4	<0.4
Zinc transporter Ab (U/mL)	0–15.0	137.6	53.8
GAD Ab (IU/mL)	0–5.0	<5.0	<5.0
Serum glucose (mg/dL)	70–100	397
Glucose tolerance test
0 min/fasting			93
60 min			207
120 min			184
C-peptide (ng/mL)	0.8–3.5	1.4
0 min/fasting			1.0
120 min			3.8
Insulin (µIU/mL)	3–19	10
0 min/fasting			6
120 min			20

*For his age and Tanner stage.

Ab, antibody; GAD Ab, glutamic acid decarboxylase antibody; HbA1c, hemoglobin A1c; IA-2 Ab, islet antigen 2 antibody; IGF-1, insulin-like growth factor-1; rhGH, recombinant human growth hormone; Zn Ab, zinc transporter antibody.