Table 2:
Effect sizes, Akaike Information Criterion, and adjusted R2 for forward model selection of NAA/Cr in WM and deep GM with T1D covariates
| Tissue | HbA1c | DKA | HbA1c x DKA | Age | Sex | Duration | Akaike | aR2 |
|---|---|---|---|---|---|---|---|---|
| WM | –0.086a | – | – | – | – | – | 17.581 | 0.291 |
| –0.080b | –0.095 | – | – | – | – | 19.083 | 0.273 | |
| –0.171a,c | –1.142b,c | 0.130b,c | – | – | – | 15.373c | 0.394c | |
| –0.169a | –1.156b | 0.131b | –0.009 | – | – | 17.298 | 0.365 | |
| –0.187a | –1.209b | 0.141b | –0.001 | 0.175 | – | 17.086 | 0.389 | |
| –0.187a | –1.267b | 0.144b | –0.005 | 0.189 | 0.012 | 18.799 | 0.362 | |
| Deep GM | –0.016c | – | – | – | – | – | –29.356c | 0.061c |
| –0.018 | 0.034 | – | – | – | – | –27.785 | 0.034 | |
| –0.027 | –0.065 | 0.012 | – | – | – | –26.087 | –0.001 | |
| –0.029 | –0.043 | 0.010 | 0.011 | – | – | –24.800 | –0.023 | |
| –0.027 | –0.035 | 0.009 | 0.010 | –0.018 | – | –22.922 | –0.075 | |
| –0.028 | –0.086 | 0.011 | 0.007 | –0.005 | 0.011 | –22.194 | –0.079 |
Note:—The en dash indicates that term was not included in model; aR2, adjusted R2.
a
P < .005.
b
P < .05.
c
Model with lowest Akaike Information Criterion.