Table 2.

Univariate and multivariate logistic regression analyses for total prostate cancer risk.

	Univariate logistic regression				Multivariate logistic regression
	OR	95% CI		p	OR	95% CI		p
		Lower	Upper			Lower	Upper
Age, yr
≤65				<0.0001				0.001
66–70	2.510	1.585	3.974	<0.0001	2.850	1.633	4.973	<0.0001
71–75	2.157	1.400	3.322	<0.0001	1.642	0.959	2.810	0.070
>75	2.822	1.798	4.429	<0.0001	2.340	1.307	4.191	0.004
PSA, ng/mL
≤6				<0.0001
6.1–8	1.781	1.101	2.881	0.019
8.1–10	1.920	1.143	3.225	0.014
>10	3.701	2.454	5.582	<0.0001
PSA density, ng/mL/mL
≤0.15				<0.0001				<0.0001
0.151–0.29	3.012	1.989	4.561	<0.0001	2.350	1.501	3.680	<0.0001
0.3–0.44	5.857	2.852	12.028	<0.0001	3.887	1.797	8.406	0.001
>0.45	16.343	8.081	33.049	<0.0001	9.445	4.341	20.547	<0.0001
TRUS prostate volume, mL
<20				<0.0001
21–30	1.118	0.456	2.743	0.808
31–40	1.184	0.503	2.787	0.698
>40	0.342	0.155	0.753	0.008
mpMRI prostate volume, mL
<20				<0.0001
21–30	1.207	0.423	3.443	0.726
31–40	0.528	0.199	1.404	0.201
>40	0.288	0.114	0.727	0.008
DRE
Positive	3.031	2.150	4.274	<0.0001	1.357	0.880	2.093	0.167
PI-RADS score
PI-RADS 2				<0.0001				<0.0001
PI-RADS 3	1.333	0.707	2.516	0.374	1.242	0.613	2.516	0.547
PI-RADS 4	2.534	1.413	4.544	0.002	2.077	1.090	3.957	0.026
PI-RADS 5	10.264	5.391	19.540	<0.0001	4.847	2.357	9.970	<0.0001

CI = confidence interval; DRE = digital rectal examination; mpMRI = multiparametric magnetic resonance imaging; OR = odds ratio; PI-RADS = Prostate Imaging Reporting and Data System; PSA = prostate-specific antigen; TRUS = transrectal ultrasound.