Table 1. Overview of volunteer characteristics infected with PfSPZ Challenge 7G8 and parasite counts determined either by thick blood smear (TBS) or qPCR at the day of treatment/sampling.
| Volunteer ID | Sex | Year of birth | Trial phase/Immunization | No. of 7G8 sporozoites | Day of treatment/sampling | Parasites/μL (TBS) | Parasites/mL (qPCR) |
|---|---|---|---|---|---|---|---|
| M08.1D | m | 1976 | Dose optimization | 800 | 13 | 11 | 8,216 |
| M08.2D | m | 1988 | Dose optimization | 800 | 12 | 7 | 717 |
| M16.1D | m | 1992 | Dose optimization | 1,600 | 12 | 30 | 8,593 |
| M32.1D | m | 1989 | Dose optimization | 3,200 | 11 | 0* | 3,671 |
| M32.2D | m | 1993 | Dose optimization | 3,200 | 12 | 89 | 3,956 |
| M32.3P | f | 1992 | Regimen verification (placebo) | 3,200 | 10 | 3 | 3,560 |
| M32.4P | f | 1994 | Regimen verification (placebo) | 3,200 | 11 | 0* | 1,757 |
| M32.5P | m | 1991 | Regimen verification (placebo) | 3,200 | 11 | 0* | 3,666 |
| C32.1P | f | 1992 | Regimen verification (placebo) | 3,200 | 11 | 4* | 15,559 |
| C32.2P | m | 1993 | Regimen verification (placebo) | 3,200 | 10 | 0* | 8,955 |
| C32.3P | m | 1997 | Regimen verification (placebo) | 3,200 | 11 | 0 | 11,555 |
* Below lower limit of detection of TBS