Figure 2. Microphase separation of active and inactive chromatin regions.

Left: Chromatin as a multiblock copolymer with active (green) and inactive blocks (red) comprising $N_{\mathrm{A}}$ and $N_{\mathrm{B}}$ monomers, respectively. Right: Core-shell organization of chromatin. The cores (red area) are composed of condensed, inactive blocks of chromatin and the shells (green area) are composed of active blocks of chromatin that are less condensed that the cores in the absence of chromatin-binding protein complexes that cause them to be even more swollen.