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. 2023 Jun 28;14:1211730. doi: 10.3389/fimmu.2023.1211730

Figure 2.

Figure 2

Tumor conditioned media stimulates inflammasomes in macrophages (A) IL-1β production in bone marrow derived macrophages primed with LPS and treated with either poly (dA: dT) or TRAMPC2 prostate cancer conditioned media (CM). (B) IL-1β production from PMA and LPS treated THP-1 treated with CM from A549, Hela or MCF7 cells (+) or DMEM only for 24 h (-). (C, D) Inflammasome components from PMA and LPS treated THP-1 treated with CM from A549 cells. Graph shows the quantification of immunoblots using Image J (fold change vs Actin) *p<0.05; **p<0.01; ***p<0.001; ****p<0.0001. Data represents the mean ± SEM of at 3-5 independent experiments.