Table 2.
Comparison of indices of thyroid hormones and deiodination.
| Variable | Control |
CFS patients |
||
|---|---|---|---|---|
| Control |
SELENOP aAb (−) |
SELENOP aAb (+) |
p-valueb | |
| n = 119a | n = 99a | n = 12a | ||
| TSH (mU/L) | 1.59 (1.04) | 1.44 (0.81) | 1.25 (0.80) | 0.44 |
| (Missing) | 21 | 12 | 2 | |
| FT4(pmol/L) | 15.6 (2.7) | 15.8 (3.2) | 17.9 (1.9) | 0.005 |
| (Missing) | 20 | 12 | 2 | |
| FT3 (pmol/L) | 5.20 (1.25) | 5.20 (1.10) | 4.85 (1.25) | 0.12 |
| (Missing) | 20 | 12 | 2 | |
| TT4 (nmol/L) | 72.0 (15.3) | 62.8 (27.6) | 64.1 (17.1) | <0.001 |
| (Missing) | 20 | 12 | 2 | |
| TT3 (nmol/L) | 1.60 (0.40) | 1.40 (0.68) | 1.45 (0.50) | <0.001 |
| (Missing) | 20 | 13 | 2 | |
| rT3 (nmol/L) | 0.23 (0.07) | 0.22 (0.08) | 0.28 (0.11) | 0.25 |
| (Missing) | 20 | 12 | 2 | |
| % TT4 | 97.6 (0.4) | 97.5 (0.4) | 97.9 (0.2) | 0.033 |
| (Missing) | 20 | 13 | 2 | |
| % TT3 | 2.14 (0.44) | 2.07 (0.40) | 1.80 (0.38) | 0.005 |
| (Missing) | 20 | 13 | 2 | |
| % rT3 | 0.30 (0.09) | 0.34 (0.15) | 0.35 (0.12) | <0.001 |
| (Missing) | 20 | 13 | 2 | |
| TT3/TT4 | 2.19 (0.46) | 2.12 (0.42) | 1.84 (0.39) | 0.005 |
| (Missing) | 20 | 13 | 2 | |
| FT3/FT4 | 34.0 (8.5) | 32.6 (5.6) | 27.7 (3.7) | <0.001 |
| (Missing) | 20 | 12 | 2 | |
| rT3/TT4 | 0.31 (0.09) | 0.34 (0.15) | 0.35 (0.12) | <0.001 |
| (Missing) | 20 | 12 | 2 | |
| rT3/TT3 | 1.47 (0.57) | 1.76 (0.94) | 1.86 (1.18) | <0.001 |
| (Missing) | 20 | 13 | 2 | |
| TT3/FT3 | 0.31 (0.05) | 0.28 (0.12) | 0.25 (0.08) | 0.002 |
| (Missing) | 20 | 13 | 2 | |
| TT4/FT4 | 46.3 (10.4) | 40.8 (16.9) | 37.9 (12.6) | <0.001 |
| (Missing) | 20 | 12 | 2 | |
| SPINA GT (pmol/s) | 2.08 (1.01) | 1.65 (1.14) | 2.04 (0.84) | 0.007 |
| (Missing) | 21 | 12 | 2 | |
| SPINA GD (nmol/s) | 15.8 (4.5) | 13.6 (6.2) | 13.1 (5.5) | <0.001 |
| (Missing) | 20 | 13 | 2 | |
| Iodine urine (μg/d) | 89.0 (54.9) | 58.9 (45.2) | 43.2 (16.0) | <0.001 |
| (Missing) | 32 | 15 | 2 | |
| SPINA GD x Iodine urine | 1329.0 (1006.7) | 665.3 (675.6) | 481.8 (258.4) | <0.001 |
| (Missing) | 32 | 16 | 2 | |
a
Median (IQR).
b
Kruskal-Wallis rank sum test.