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. 2023 Jul 12;14:4083. doi: 10.1038/s41467-023-39416-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A–F Changes in the prevalence of MDR isolates (resistant to 3 or more antibiotics) and strain composition in longitudinally sampled patients with mixed strain populations. Percentage of MDR isolates is shown between the first and last sampling points. Colour blocks between these sampling points indicate patient antibiotic use. The inset pie charts show the proportion of STs at each time point (inner ring), and the contribution of these STs to MDR (outer ring). Each inset pie chart is labelled with the day of sampling it corresponds to. A Patient 8, B Patient 15, C Patient 17, D Patient 10, E Patient 16, F Patient 18. G For these five mixed strain population patients where resistance increases, we partitioned the increases in the prevalence of MDR isolates into changes in ST composition and changes in multi-drug resistance within strains. Numbers indicate patient ID. The raw data is presented in the source data file.