Table 3.

Characteristics of CUP patients who received systemic therapy.

	All CUP patients who received systemic therapy (n = 100)	Empirical chemotherapy only (n = 54)	Site-specific, targeted therapy or immunotherapy (n = 46)
Median age (years)	63	63	63
Sex
Female	54	31 (57%)	23 (50%)
Male	46	23 (43%)	23 (50%
Charlson comorbidity index
<3	94	50 (93%)	44 (96%)
≥3	6	4 (7%)	2 (4%)
ECOG performance status
0–1	88	47 (87%)	41 (89%)
≥2	10	6 (11%)	4 (9%)
Unknown	2	1 (2%)	1 (2%)
Likely tissue of origin
Yes	38	7 (13%)	31 (67%)
No	62	47 (87%)	15 (33%)
Favourable subtype
Yes	33	5 (9%)	28 (61%)
No	67	49 (91%)	18 (39%)

CUP cancer of unknown primary, ECOG Eastern Cooperative Oncology Group.