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. 2023 Jul 12;10:449. doi: 10.1038/s41597-023-02330-9

Table 2.

Summary of templates and datasets released, raters, and anatomical fiducial (AFID) protocol performances.

Template or Dataset Brief Description Field Strength (T) Raters (N) Total number of AFID annotations References
Imaging AFID Annotations
MNI2009bAsym A population group template consisting  of 152 individuals commonly used in the neuroimaging literature 1.5 8 novices 8 × 4 (1,024 individual points) Fonov et al.16 Lau et al.17
MNIColin27 A template of a single healthy control subject (N = 1) scanned 27 times and averaged together 1.5 Holmes et al.18
Agile12v2016 An ultra-high field template consisting of 12 healthy control averaged subjects created at the Centre for Functional and Metabolic Mapping at Western University 7 Lau et al.17
BigBrainSym Ultra-high resolution histological 3D model of the brain (BigBrain) registered to MNI2009bSym space N/A; histological 2 experts 2 × 1 (64 individual points) Amunts et al.19 Xiao et al.6
MNI2009bSym The symmetric version of the MNI2009bAsym template 1.5 Fonov et al.16
PD-25 A multi-contrast MNI template of a Parkinson’s disease (PD) cohort 3 Xiao et al.20 N/A
TemplateFlow A centralized resource of open-access templates for neuroimaging studies (tpl-MNI152 -Lin, NLin2009cAsym, NLin2009cSym, NLin6Asym, NLin6Sym, tpl-MNI305, tpl-OASIS30ANTs, tpl-fsaverage) 3+ 4 total: 1 expert and 3 novices 4 × 1 (128 individual points) Ciric et al.22 N/A
AFIDs-HCP30 A subset of N = 30 healthy control subject images from the Human Connectome Project (HCP) dataset 3 5 experts 3 × 30 (2,880 individual points) Van Essen et al.13 N/A
AFIDs-OASIS30 A subset of N = 30 cognitively intact control subject images from the OASIS-1 database selected to exhibit a wide range of normal anatomical variability 3 9 total: 1 expert and 8 novices Marcus et al.14 Lau et al.2
LHSCPD A set of N = 40 PD patient images acquired at University Hospital (Western University, Canada) 1.5 5 total: 2 expert and 3 novices 5 × 40 (6,400 individual points) Abbass et al.3
SNSX A set of N = 32 control subject images acquired at the Centre for Functional and Metabolic Mapping atWestern University 7 9 total: 3 expert and 6 novices 3 × 32 (3,072 individual points) Lau et al.7