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. 2023 May 1;37(8):6062–6070. doi: 10.1007/s00464-023-09980-1

Table 2.

Surgery-related factors and risk for vasopressor agents

Variable Vasopressor agents (n = 579) No vasopressor agents (n = 969) p value
Missing Missing
Could vasopressor agents be stopped? 322 (56%)
Epidural 209 (37%) 291 (31%) 0.010
Goal Directed Therapy 145 (26%) 160 (16%)  < 0.001
Intraoperative event* 92 (16%) 126 (13%) 0.065
Temperature 36 degrees 109 (19%) n = 1 195 (20%) n = 7 0.272
Glucose > 10 mmol/L 52 (9%) n = 13 76 (8%) n = 49 0.299
Antibiotics < 15 or > 60 min prior incision 132 (24%) n = 17 221 (24%) n = 38 0.482
Blood loss > 500 mL 31 (7%) n = 35 37 (2%) n = 42 0.003
Oxygen < 94% 13 (22%) 14 (15%) 0.173
Mean arterial pressure < 65 53 (9%) 86 (9%) 0.463
Urine production < 30 mL/h 98 (18%) 156 (17%) 0.350
OR time > 180 min 167 (29%) 288 (30%) 0.379
Hemoglobin 0.001
 Men < 7 mmol/L 48 (9%) 42 (4%)  < 0.001
 Woman < 6.5 mmol/L 111 (21%) 106 (12%)
Surgical approach 0.113
 Open 95 (16%) 136 (14%)
 Laparoscopy 451 (78%) 779 (80%)
 Laparoscopy with conversion 31 (5%) 53 (5%) 0.223
Fluid administration 0.169
  < 250 mL/h 89 (15%) 120 (12%)
 250–1000 mL/h 453 (78%) 773 (80)
  > 1000 mL/h 37 (6%) 76 (8%)
Fluid administration > 500 mL/h 236 (41%) 465 (48%) 0.003
Blood transfusion  < 0.001
 1 packed cells 21 (4%) 10 (1%)
 2 packed cells 3 (0.5%) 1 (0.1%)

Bold values indicate significance of p value (p < 0.005)

Data are presented as number (%) or as medians (range) for categorical and continuous variables, respectively. N is number of inclusions if due to missing data this deviates from total

A p < 0.05 was considered statistically significant

*Intraoperative events include: hypoxic events, hypertension, hypercarbia, bradycardia, hypotension, embolism, reanimation, more extensive resection than planned, serosa lesions, bladder and ureteral injuries, intraoperative bleeding, splenectomy or bleeding