Table 2.
Association between diet inflammatory index and subsequent MS conversion and relapse hazard, AusLong Study, 2003–present.
| Relapses | |||
|---|---|---|---|
| Failures/person-years (rate) | aHR (95%CI) * | p | |
| DII ScoreContinuous form | 1.18 (1.03, 1.37) | 0.02 | |
| DII ScoreCategorical form | |||
| −2.176 to 0.241 | 58/212.69 (0.27) | 1.00 (Ref) | |
| 0.242 to 1.864 | 94/191.32 (0.49) | 1.59 (0.96, 2.62) | 0.07 |
| 1.865 to 2.682 | 94/182.94 (0.51) | 1.32 (0.79, 2.22) | 0.29 |
| >2.682 | 62/179.52 (0.34) | 1.98 (1.02, 3.75) | 0.04 |
| Test for trend: | 0.13 | ||
| E-DII ScoreContinuous form | 0.97 (0.95, 0.10) | 0.02 | |
| E-DII ScoreCategorical form | |||
| −3.150 to −5.710 | 76/190.78 (0.40) | 1.00 (Ref) | |
| −5.711 to 0.713 | 66/195.45 (0.34) | 1.96 (1.02, 3.76) | 0.04 |
| 0.714 to 1.835 | 79/201.90 (0.39) | 2.19 (1.03, 4.63) | 0.04 |
| >1.835 | 87/178.35 (0.49) | 2.24 (1.16, 4.33) | 0.02 |
| Test for trend: | 0.03 | ||
Both DII and E-DII models were restricted to those with reliable dietary reporting.
The DII variables were categorised using quartiles.
*
DII Models were adjusted for age at baseline, sex, total energy intake and stratified by study site. E-DII Models were adjusted for age at baseline, sex, and study site. EDII = Dietary Inflammatory Index created with energy-adjusted global database; MS = multiple sclerosis.