Table 3.
Diet inflammatory index and annualised EDSS change: the association between the indices at the 5- and 10-year reviews and annualised change in EDSS to the 5- and 10-year reviews, AusLong Study, 2003–present.
| N 5 | N 10 | Annualised EDSS change | ||
|---|---|---|---|---|
| aβ* (95% CI) | P | |||
| DII ScoreContinuous form | 180 | 176 | −0.02 (−0.06, 0.01) | 0.22 |
| DII ScoreCategorical form | ||||
| −2.176 to 0.241 | 39 | 36 | 0.09 (−0.27, 0.45) (Ref)** | |
| 0.242 to 1.864 | 50 | 39 | −0.12 (−0.24, −0.01) | 0.06 |
| 1.865 to 2.682 | 39 | 45 | −0.14 (−0.28, −0.00) | 0.05 |
| >2.682 | 52 | 56 | −0.09 (−0.24, 0.06) | 0.15 |
| Test for trend: | 0.31 | |||
| E-DII ScoreContinuous form | 180 | 176 | −0.01 (−0.03, 0.02) | 0.65 |
| E-DII ScoreCategorical form | ||||
| −3.150 to −5.710 | 49 | 40 | 0.09 (−0.12, 0.31) (Ref)** | |
| −5.711 to 0.713 | 42 | 48 | +0.02 (−0.09, 0.15) | 0.62 |
| 0.714 to 1.834 | 42 | 46 | −0.02 (−0.14, 0.10) | 0.71 |
| >1.834 | 47 | 42 | +0.01 (−0.11, 0.13) | 0.84 |
| Test for trend: | 0.94 | |||
DII models were adjusted for dietary misreporting, employment status, age, energy intake, relapse at present review (yes/no) and sex. E-DII models were adjusted for dietary reporting, relapse at present review (yes/no), age, and sex.
Results for categorical variables are presented as the mean absolute change (95% CI) of reference level of the predictor, then mean change (95% CI) of other levels relative to reference. Transformed (Box-Cox; back-transformed) linear mixed-effects models for repeated measures were used; results were then back-transformed and presented on their original scale at the mean of model covariates. N5 and N10 are the number of people in each category at the 5- and 10-year reviews, respectively. CI = confidence interval; EDII = Dietary Inflammatory Index created with energy-adjusted global database.