Table 3.
Comparison Between Weaning Groups, and Between the Mortality Outcome 28 Days Groups According to Oxygenation Parameters, Circulatory Support, and Urine Output.
| Parameters | Total (n = 90) |
Weaning | p | Mortality Outcome 28 days | p | ||
|---|---|---|---|---|---|---|---|
| Weaning Success 50 (55.6%) |
Weaning Failure 40 (44.4%) |
Survival 45 (50%) |
Died 45 (50%) |
||||
| PaO2 Median (Min.–Max.) |
56 (32–92) | 59 (32–88) | 54.5 (37–92) | .627 | 59 (36–88) | 55 (32–92) | .060 |
| FiO2 Mean ± SD | 0.83 ± 0.19 | 0.84 ± 0.19 | 0.82 ± 0.19 | .617 | 0.83 ± 0.20 | 0.83 ± 0.19 | .913 |
| P/F ratio Median (Min.–Max.) |
67 (37–135) | 67 (44–135) | 66.5 (37–130) | .410 | 67 (44–135) | 65 (37–130) | .208 |
| SaO2 Mean ± SD | 84.16 ± 8.70 | 84.88 ± 8.94 | 83.25 ± 8.41 | .380 | 85.24 ± 8.71 | 83.07 ± 8.64 | .237 |
| ScvpO2Mean ± SD | 64.81 ± 11.35 | 65.50 ± 10.46 | 63.95 ± 12.46 | .523 | 65.31 ± 10.63 | 64.31 ± 12.13 | .678 |
| PA_aDO2 Median (Min.–Max.) |
558.4 (229.8–647) |
575 (229.8–640) |
521.1 (272.8–647) |
.548 | 575 (229.8–640) |
556.7 (272.8–647) |
.289 |
| PCO2 Median (Min.–Max.) |
33.5 (17–117) | 44 (17–117) | 29 (19–97) | .059 | 52 (17–117) | 30 (19–97) | .040* |
| Lung compliance | |||||||
| Static (Mean ± SD) | 26.10 ± 6.64 | 26.38 ± 6.37 | 25.75 ± 7.03 | .657 | 26.36 ± 6.10 | 25.84 ± 7.20 | .717 |
| Dynamic (Mean ± SD) | 45.06 ± 7.06 | 46.54 ± 6.40 | 43.20 ± 7.47 | .025* | 46.64 ± 6.46 | 43.47 ± 7.34 | .032* |
| PEEP needed: Median (Min.–Max.) |
10 (0–12) | 10 (8–12) | 10 (0–12) | .261 | 10 (8–12) | 10 (0–12) | .240 |
| Raw (Mean ± SD) | 14.61 ± 5.36 | 14.62 ± 5.38 | 14.60 ± 5.39 | .986 | 14.87 ± 5.55 | 14.36 ± 5.21 | .653 |
| P. plat (Mean ± SD) | 20.02 ± 3.84 | 19.84 ± 3.51 | 20.25 ± 4.25 | .618 | 19.71 ± 3.57 | 20.33 ± 4.12 | .446 |
| P. peak (Mean ± SD) | 34.63 ± 4.71 | 34.46 ± 4.24 | 34.85 ± 5.29 | .699 | 34.58 ± 4.34 | 34.69 ± 5.11 | .912 |
| Circulatory support | |||||||
| Yes (noradrenaline) | 37 (41.1%) | 15 (30.0%) | 22 (55.0%) | .017* | 14 (31.1%) | 23 (51.1%) | .054 |
| Dose (mcg/kg) Median (Min.–Max.) |
0 (0–300) | 0 (0–300) | 50 (0–200) | .038* | 0 (0–300) | 50 (0–200) | .104 |
| Urine output | |||||||
| Mean ± SD | 1197.8 ± 474.5 | 1344 ± 453.6 | 1015 ± 440.0 | .001* | 1371.1 ± 435.2 | 1024.4 ± 452.4 | <.001* |
Abbreviations: PEEP = Positive End Expiratory Pressure; Raw = airway resistance; P. plat = plateau pressure; P peak = peak pressure.
PA_aDO2 = A-a Gradient (PA-aO2) (A-aDO2) Alveolar-arterial O2 Tension Difference.
PaO2/FiO2 ratio is the ratio of arterial oxygen partial pressure (PaO2 in mmHg) to fractional inspired oxygen.