TABLE 2.
Bivariate regression analyses of Mental and Physical Fatigue subscales of Multidimensional Fatigue Inventory on demographic, clinical, motor, and extra‐motor variables
| Mental fatigue | Physical fatigue | |||||||
|---|---|---|---|---|---|---|---|---|
| Variables | B | SE | β | p | B | SE | β | p |
| Demographics | ||||||||
| Age | 0.12 | 0.04 | 0.26 | <.01 | 0.07 | 0.04 | 0.15 | .08 |
| Education, years | –0.11 | 0.08 | –0.11 | .20 | 0.00 | 0.08 | 0.00 | .96 |
| Sex a | 0.17 | 0.80 | 0.01 | .83 | 1.25 | 0.75 | 0.14 | .10 |
| Clinical and motor features | ||||||||
| Disease duration, months | 0.01 | 0.01 | 0.07 | .39 | 0.01 | 0.01 | 0.08 | .31 |
| ALSFRS‐R total score | 0.01 | 0.05 | 0.02 | .77 | –0.04 | 0.05 | –0.07 | .38 |
| ALSFRS‐R subscores | ||||||||
| Bulbar | 0.34 | 0.19 | 0.15 | .08 | 0.11 | 0.19 | 0.05 | .53 |
| Fine motor | 0.02 | 0.12 | 0.01 | .85 | –0.01 | 0.11 | –0.01 | .87 |
| Gross motor | –0.09 | 0.12 | –0.07 | .42 | –0.29 | 0.11 | –0.22 | .01 |
| Respiratory | 0.10 | 0.22 | 0.04 | .62 | –0.06 | 0.21 | –0.02 | .75 |
| Upper Motor Neuron score | –0.13 | 0.09 | –0.13 | .14 | 0.00 | 0.08 | 0.00 | .92 |
| Patients under NIV b | –1.90 | 1.45 | –0.11 | .19 | 0.25 | 0.13 | 0.01 | .85 |
| Patients with PEG b | –0.81 | 2.60 | –0.02 | .75 | 2.90 | 2.46 | 0.10 | .24 |
| Patients in Riluzole therapy b | 2.87 | 1.52 | 0.16 | .06 | 0.01 | 1.46 | 0.00 | .99 |
| Extra‐motor features | ||||||||
| ECAS total score | –0.03 | 0.02 | –0.12 | .15 | –0.03 | 0.02 | –0.14 | .10 |
| ECAS subscores | ||||||||
| Executive functions | –0.03 | 0.04 | –0.06 | .49 | –0.05 | 0.04 | –0.11 | .19 |
| Fluency | –0.01 | 0.06 | –0.02 | .78 | –0.10 | 0.06 | –0.14 | .09 |
| Language | –0.08 | 0.08 | –0.08 | .33 | –0.05 | 0.08 | –0.05 | .54 |
| Memory | –0.20 | 0.08 | –0.21 | .01 | –0.06 | 0.07 | –0.07 | .42 |
| Visuospatial abilities | –0.36 | 0.27 | –0.11 | .19 | –0.14 | 0.26 | –0.04 | .58 |
| Beck Depression Inventory‐II | –0.02 | 0.04 | –0.04 | .60 | 0.08 | 0.04 | 0.17 | .05 |
| STAI form Y‐1 | 0.00 | 0.03 | 0.01 | .88 | 0.07 | 0.03 | 0.21 | .01 |
| DAS total score | 0.07 | 0.04 | 0.16 | .06 | 0.00 | 0.04 | –0.01 | .85 |
| DAS subscales: | ||||||||
| Executive | 0.27 | 0.09 | 0.24 | <.01 | 0.02 | 0.09 | 0.02 | .76 |
| Emotional | 0.04 | 0.10 | 0.03 | .67 | –0.09 | 0.09 | –0.08 | .35 |
| Cognitive and Behavioral Initiation | 0.05 | 0.07 | 0.07 | .41 | 0.01 | 0.06 | 0.01 | .88 |
| Epworth Sleepiness Scale | 0.01 | 0.12 | 0.00 | .92 | 0.00 | 0.11 | 0.00 | .95 |
Note. Statistically significant variables are shown in bold.
a
Coded as: 0 = male, 1 = female.
b
Coded as: 0 = no, 1 = yes.
B, unstandardized beta coefficient; SE, standard error; β, standardized beta coefficient; ALSFRS‐R, ALS Functional Rating Scale—Revised; NIV, noninvasive ventilation; PEG, Percutaneous Endoscopic Gastrostomy; ECAS, Edinburgh Cognitive and Behavioral ALS Screen; DAS, Dimensional Apathy Scale; STAI, State‐Trait Anxiety Inventory; MFI, Multidimensional Fatigue Inventory.