Table 1.
Clinical characteristics of melioidosis patients.
| Characteristics | Derivation cohort (N = 78) | External validation cohort (N = 191) |
|---|---|---|
| Demographics | ||
| Age in years, median (IQR) | 58 (48–68) | 54 (46–64) |
| Male sex, N (%) | 60 (77) | 132 (69) |
| Pre-existing conditions | ||
| Charlson Comorbidity Index, median (IQR) | 3 (2–5) | 2 (1–3) |
| Diabetes, N (%) | 56 (72) | 88 (46) |
| Chronic kidney disease, N (%) | 20 (26) | 26 (14) |
| Chronic lung disease, N (%) | 7 (9) | 15 (8) |
| Chronic liver disease, N (%) | 2 (3) | 7 (4) |
| Chronic cardiovascular disease, N (%) | 6 (8) | 11 (6) |
| Cancer, N (%) | 5 (6) | 3 (2) |
| Human immunodeficiency virus, N (%) | 2 (3) | 0 (0) |
| Days to enrollment, median (IQR) | 4 (3–5) | 1 (0–1) |
| Organ failure scorea | 2 (0–5) | - |
| Modified SOFA score, median (IQR) | - | 5 (2–9) |
| Died within 28 days, N (%) | 29 (37) | 98 (51) |
a
Organ failure score was derived from the available components of a SOFA score using clinical and laboratory data within the first 24 h of admission.