Table 5.
Association of biomarkers with 28-day mortality in the external validation cohort.
| Biomarker (log10) | Unadjusted | Baseline-adjusteda | Baseline + SOFA-adjustedb | ||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
| IL-1R2 | 35.9 | 13.8–93.3 | <0.001 | 47.4 | 17.0–132.3 | <0.001 | 28.2 | 7.8–101.7 | <0.001 |
| sTREM-1 | 18.4 | 8.0–42.0 | <0.001 | 18.4 | 7.9–42.9 | <0.001 | 8.1 | 3.0–22.3 | <0.001 |
a
Adjusted for age, sex, and Charlson Comorbidity Index.
b
Adjusted for age, sex, Charlson Comorbidity Index, and modified SOFA score.